Conditional Fragment Ion Probabilities Improve Database Searching for Nonmonoisotopic Precursors
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DOI: 10.1021/acs.jproteome.2c00247
Abstract: Stochastic, intensity-based precursor isolation can result in isotopically enriched fragment ions. This problem is exacerbated for large peptides and stable isotope labeling experiments using deuterium or 15N. For stable isotope labeling experiments, incomplete and ubiquitous… read more here.
Keywords: database searching; fragment ion; ion probabilities; ion ... See more keywords