Remote Control of the Synthesis of a [2]Rotaxane and its Shuttling via Metal‐Ion Translocation
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DOI: 10.1002/open.201900293
Abstract: Abstract Remote control in an eight‐component network commanded both the synthesis and shuttling of a [2]rotaxane via metal‐ion translocation, the latter being easily monitored by distinct colorimetric and fluorimetric signals. Addition of zinc(II) ions to… read more here.
Keywords: remote control; ion translocation; metal; ion ... See more keywords
Structural bases for Na+-Cl− cotransporter inhibition by thiazide diuretic drugs and activation by kinases
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DOI: 10.1038/s41467-024-51381-y
Abstract: The Na+-Cl− cotransporter (NCC) drives salt reabsorption in the kidney and plays a decisive role in balancing electrolytes and blood pressure. Thiazide and thiazide-like diuretics inhibit NCC-mediated renal salt retention and have been cornerstones for… read more here.
Keywords: ncc ion; activation; thiazide like; ion translocation ... See more keywords
Transmembrane Segment XI of the Na+/H+ Antiporter of S. pombe is a Critical Part of the Ion Translocation Pore
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DOI: 10.1038/s41598-017-12701-z
Abstract: The Na+/H+ exchanger of the plasma membrane of S. pombe (SpNHE1) removes intracellular sodium in exchange for an extracellular proton. We examined the structure and functional role of amino acids 360–393 of putative transmembrane (TM)… read more here.
Keywords: part ion; amino acids; transmembrane segment; ion translocation ... See more keywords