β-Ionone represses renal cell carcinoma progression through activating LKB1/AMPK-triggered autophagy.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23331
Abstract: β-Ionone, the end ring analog of β-carotenoids, has been proven to have an antitumor effect in a variety of cancers. In this study, we investigated the impact of β-ionone on renal cell carcinoma (RCC) cell… read more here.
Keywords: cell; cell carcinoma; renal cell; ionone ... See more keywords
Molecular Hybridization-Guided Construction of Convolutamydine A-fused β-Ionone Scaffolds and their Biological Evaluation for Anticancer Activities
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Heterocyclic Chemistry"
DOI: 10.1002/jhet.3027
Abstract: Described herein is a facile and efficient methodology toward the synthesis of novel convolutamydine A-incorporated β-ionone scaffold 3 from an Aldol addition event of β-ionone to isatins via enamine Et2NH catalysis. Products featuring a quaternary… read more here.
Keywords: convolutamydine; molecular hybridization; ionone; guided construction ... See more keywords
One-pot synthesis of dihydro-β-ionone from carotenoids using carotenoid cleavage dioxygenase and enoate reductase
Sign Up to like & getrecommendations! Published in 2022 at "Bioprocess and Biosystems Engineering"
DOI: 10.1007/s00449-022-02707-x
Abstract: Dihydro-β-ionone is a characteristic aroma compound of Osmanthus fragrans and is widely applied in the flavor & fragrance industry. However, the main focus is on chemical synthesis due to the metabolic pathways of dihydro-β-ionone is… read more here.
Keywords: synthesis; one pot; ionone; enoate reductase ... See more keywords
A New Dimeric Ionone from the Unripe Fruits of Capsicum annuum var. conoides
Sign Up to like & getrecommendations! Published in 2018 at "Chemistry of Natural Compounds"
DOI: 10.1007/s10600-018-2401-4
Abstract: Red pepper, Capsicum annuum (Solanaceae), is used as a spice all over the world. Red pepper is studied actively because its pungent principal component, capsaicin, has a dietary effect, analgesic activity, and antioxidant activity [1].… read more here.
Keywords: var conoides; capsicum annuum; annuum var; unripe fruits ... See more keywords
A New α-Ionone from Michelia champaca
Sign Up to like & getrecommendations! Published in 2020 at "Chemistry of Natural Compounds"
DOI: 10.1007/s10600-020-03043-w
Abstract: A new α-ionone, (Z)-4-hydroxy-3,5,5-trimethyl-4-(3′-oxobut-1′-enyl)cyclohex-2-enone (1) was isolated from the flower of Michelia champaca L. The structure of the new α-ionone was elucidated by chemical and physical evidence. read more here.
Keywords: michelia champaca; chemistry; ionone michelia; ionone ... See more keywords
A New Ionone from Emilia sonchifolia
Sign Up to like & getrecommendations! Published in 2021 at "Chemistry of Natural Compounds"
DOI: 10.1007/s10600-021-03444-5
Abstract: A new 4,5-epoxy-4,5-dihydro-α-ionone, emilifodione (1), was isolated from the leaves of Emilia sonchifolia (L.) DC. ex DC. (Asteraceae). The structure of the new ionone was elucidated by chemical and physical evidence. read more here.
Keywords: new ionone; ionone emilia; ionone; chemistry ... See more keywords
Application of Stable Isotope Tracing to Elucidate Metabolic Dynamics During Yarrowia lipolytica α-Ionone Fermentation
Sign Up to like & getrecommendations! Published in 2020 at "iScience"
DOI: 10.1016/j.isci.2020.100854
Abstract: Summary Targeted metabolite analysis in combination with 13C-tracing is a convenient strategy to determine pathway activity in biological systems; however, metabolite analysis is limited by challenges in separating and detecting pathway intermediates with current chromatographic… read more here.
Keywords: application stable; metabolic dynamics; fermentation; ionone ... See more keywords
Characteristics of NtCCD1-3 from tobacco, and protein engineering of the CCD1 to enhance β-ionone production in yeast
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1011297
Abstract: Biosynthesis of β-ionone by microbial cell factories has become a promising way to obtain natural β-ionone. The catalytic activity of carotenoid cleavage dioxygenase 1 (CCD1) in cleavage of β-carotene to β-ionone severely limits its biosynthesis.… read more here.
Keywords: ionone production; ionone; ntccd1 tobacco; characteristics ntccd1 ... See more keywords
Identification of the carotenoid cleavage dioxygenase genes and functional analysis reveal DoCCD1 is potentially involved in beta-ionone formation in Dendrobium officinale
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.967819
Abstract: The carotenoids are the most widely distributed secondary metabolites in plants and can be degraded by carotenoid cleavage dioxygenase (CCD) to form apocarotenoids including an important C13 compound beta-ionone. Volatile beta-ionone can confer the violet… read more here.
Keywords: ionone; beta ionone; gene; dioxygenase ... See more keywords
Characterization of a Novel Lutein Cleavage Dioxygenase, EhLCD, from Enterobacter hormaechei YT-3 for the Enzymatic Synthesis of 3-Hydroxy-β-ionone from Lutein
Sign Up to like & getrecommendations! Published in 2021 at "Catalysts"
DOI: 10.3390/catal11111257
Abstract: 3-Hydroxy-β-ionone, a flavor and fragrance compound with fruity violet-like characteristics, is widely applied in foodstuff and beverages, and is currently produced using synthetic chemistry. In this study, a novel lutein cleavage enzyme (EhLCD) was purified… read more here.
Keywords: lutein cleavage; hydroxy ionone; ehlcd; ionone ... See more keywords
Carotenoid-Related Volatile Compounds of Tobacco (Nicotiana tabacum L.) Essential Oils
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24193446
Abstract: Tobacco (Nicotiana tabacum L.) aroma is an important attribute of tobacco quality and is influenced by a variety of minor chemical components, including carotenoid degradation products. The objectives of this work were to determine the… read more here.
Keywords: ionone 100; tobacco nicotiana; nicotiana tabacum; ionone ... See more keywords