Interaction of metal ions with tau protein. The case for a metal-mediated tau aggregation.
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DOI: 10.1016/j.jinorgbio.2019.02.007
Abstract: Tau protein aggregation and its hyperphosphorylation play an important role in the pathogenesis of Alzheimer's disease. There is also considerable evidence for the accumulation of Fe2/3+, Cu2+, and Zn2+ in the brain of Alzheimer's patients,… read more here.
Keywords: aggregation; ions tau; metal ions; interaction metal ... See more keywords