Methods for Analyzing Endoplasmic Reticulum Stress in the Trabecular Meshwork of Glaucoma Models.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7407-8_12
Abstract: The pathological mechanisms underlying increased outflow resistance at the trabecular meshwork (TM) that is responsible for elevating intraocular pressure (IOP) have not been fully delineated. Recent studies have shown that progressive accumulation of misfolded proteins… read more here.
Keywords: trabecular meshwork; endoplasmic reticulum; reticulum stress; iop elevation ... See more keywords
Single transient intraocular pressure elevations cause prolonged retinal ganglion cell dysfunction and retinal capillary abnormalities in mice.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108296
Abstract: Transient intraocular pressure (IOP) elevations are likely to occur in certain forms of glaucoma and after intravitreal injections to treat various retinal diseases. However, the impact of these transient IOP elevations on the physiology of… read more here.
Keywords: iop elevation; physiology; transient iop;
Prophylactic Effect of Oral Acetazolamide against Intraocular Pressure Elevation after Cataract Surgery in Eyes with Glaucoma.
Sign Up to like & getrecommendations! Published in 2017 at "Ophthalmology"
DOI: 10.1016/j.ophtha.2016.12.027
Abstract: PURPOSE To confirm the prophylactic effect of oral acetazolamide against increased intraocular pressure (IOP) in the period immediately after cataract surgery in eyes with primary open-angle glaucoma (POAG) and to evaluate the appropriate administration time… read more here.
Keywords: intraocular pressure; administration; oral acetazolamide; hours postoperatively ... See more keywords
Under pressure: keratoconus and intraocular pressure elevation evidence
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Ophthalmology"
DOI: 10.1080/17469899.2023.2216931
Abstract: I read with great interest the review article recently published by McMonnies [1] regarding eye rubbing-related intra-ocular pressure (IOP) elevation in the development and progression of keratoconus (KC). Although we congratulate the author for highlighting… read more here.
Keywords: elevation; pressure; eye rubbing; iop elevation ... See more keywords
Changes in Intraocular Pressure and Anterior Chamber Angle After Congenital Cataract Extraction
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DOI: 10.1097/ijg.0000000000001681
Abstract: Supplemental Digital Content is available in the text. Precis: Anterior chamber angle (ACA) narrowing continues to occur for at least 2 years after congenital cataract surgery. Risk factors for intraocular pressure (IOP) elevation after congenital… read more here.
Keywords: risk; year; surgery; cataract ... See more keywords
Changes in pulse waveforms in response to intraocular pressure elevation determined by laser speckle flowgraphy in healthy subjects
Sign Up to like & getrecommendations! Published in 2021 at "BMC Ophthalmology"
DOI: 10.1186/s12886-021-02070-7
Abstract: Background The influences of intraocular pressure (IOP) elevations on the pulse waveform in the optic nerve head (ONH) were evaluated using laser speckle flowgraphy (LSFG) in normal subjects. Methods This prospective cross-sectional study was conducted… read more here.
Keywords: intraocular pressure; laser speckle; iop elevation; elevation ... See more keywords
Ocular hypertension and severe intraocular pressure elevation after posterior subtenon injection of triamcinolone acetonide for various diseases.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2020.06.14
Abstract: AIM To evaluate and compare the incidences of ocular hypertension and severe intraocular pressure (IOP) elevation after posterior subtenon injection of triamcinolone acetonide (PSTA) for various diseases. METHODS Totally 179 eyes that had received PSTA… read more here.
Keywords: hypertension severe; ocular hypertension; severe intraocular; iop elevation ... See more keywords
Retinal electrophysiologic response to IOP elevation in brain-dead organ donors.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental eye research"
DOI: 10.2139/ssrn.4234251
Abstract: PURPOSE The relationships between intraocular pressure (IOP), ocular perfusion pressure (OPP), retinal perfusion, and retinal electrophysiologic responses have been explored experimentally across several animal models. These studies have demonstrated that elevated IOP reduces OPP, and… read more here.
Keywords: elevation; iop; eye; retinal electrophysiologic ... See more keywords
Retinal ganglion cells adapt to ionic stress in experimental glaucoma
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DOI: 10.3389/fnins.2023.1142668
Abstract: Introduction Identification of early adaptive and maladaptive neuronal stress responses is an important step in developing targeted neuroprotective therapies for degenerative disease. In glaucoma, retinal ganglion cells (RGCs) and their axons undergo progressive degeneration resulting… read more here.
Keywords: stress; sensitivity; ganglion cells; retinal ganglion ... See more keywords
Early-Onset Glaucoma in egl1 Mice Homozygous for Pitx2 Mutation
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DOI: 10.3390/biomedicines10030516
Abstract: Mutations in PITX2 cause Axenfeld–Rieger syndrome, with congenital glaucoma as an ocular feature. The egl1 mouse strain carries a chemically induced Pitx2 mutation and develops early-onset glaucoma. In this study, we characterized the glaucomatous features… read more here.
Keywords: glaucoma; early onset; pitx2 mutation; egl1 mice ... See more keywords
Association between Ocular Parameters and Intraocular Pressure Elevation during Femtosecond Laser-Assisted Cataract Surgery in Open-Angle Glaucoma and Nonglaucoma Individuals
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12020257
Abstract: In this study, we evaluate the association between biometrics and intraocular pressure (IOP) during femtosecond laser-assisted cataract surgery (FLACS) in normal patients and those with open-angle glaucoma (OAG). A retrospective cross-sectional study was conducted. A… read more here.
Keywords: elevation; intraocular pressure; iop elevation; glaucoma ... See more keywords