Alleviation of palmitic acid‐induced endoplasmic reticulum stress by augmenter of liver regeneration through IP3R‐controlled Ca2+ release
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DOI: 10.1002/jcp.26463
Abstract: The aberrant release of Ca2+ from the endoplasmic reticulum (ER) contributes to the onset of ER stress, which is closely related to the pathogenesis of non‐alcoholic fatty liver disease. We previously reported that augmenter of… read more here.
Keywords: endoplasmic reticulum; ip3r; ca2 release; stress ... See more keywords
Cardiac Specific IP3R Over-Expression: IP3ICR Contribution in Ca2+ Signaling
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DOI: 10.1016/j.bpj.2016.11.2919
Abstract: Inositol-1,4,5-trisphosphate (IP3) is a second messenger produced upon agonist binding to a G-protein coupled receptor (GPCR) and subsequently triggers SR-Ca2+ release through openings of IP3 receptors (IP3Rs). In cardiac muscle, IP3R type 2 (IP3R2) is… read more here.
Keywords: ip3r; contribution ca2; ca2; cardiac specific ... See more keywords
PFKFB3 controls acinar IP3R-mediated Ca2+ overload to regulate acute pancreatitis severity
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DOI: 10.1172/jci.insight.169481
Abstract: Acute pancreatitis (AP) is among the most common hospital gastrointestinal diagnoses; understanding the mechanisms underlying the severity of AP is critical for development of new treatment options for this disease. Here, we evaluate the biological… read more here.
Keywords: pfkfb3; pfkfb3 controls; severity; ip3r ... See more keywords