Activities and Structure-Function Analysis of Fission Yeast Inositol Pyrophosphate (IPP) Kinase-Pyrophosphatase Asp1 and Its Impact on Regulation of pho1 Gene Expression
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DOI: 10.1128/mbio.01034-22
Abstract: Expression of the fission yeast phosphate regulon is sensitive to the intracellular level of the inositol pyrophosphate (IPP) signaling molecule 1,5-IP8. IP8 dynamics are determined by Asp1, a bifunctional enzyme comprising N-terminal IPP 1-kinase and… read more here.
Keywords: pyrophosphatase; asp1; ip8; synthesis ... See more keywords
Inositol Pyrophosphate-Controlled Kinetochore Architecture and Mitotic Entry in S. pombe
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DOI: 10.3390/jof8090933
Abstract: Inositol pyrophosphates (IPPs) comprise a specific class of signaling molecules that regulate central biological processes in eukaryotes. The conserved Vip1/PPIP5K family controls intracellular IP8 levels, the highest phosphorylated form of IPPs present in yeasts, as… read more here.
Keywords: ip8; kinetochore architecture; pombe; mitotic entry ... See more keywords