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Comparable Intestinal and Hepatic First-Pass Effect of YL-IPA08 on the Bioavailability and Effective Brain Exposure, a Rapid Anti-PTSD and Anti-Depression Compound

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Published in 2020 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2020.588127

Abstract: YL-IPA08, exerting rapid antidepressant-like and anxiolytic-like effects on behaviors by translocator protein (TSPO) mediation, is a novel compound that has been discovered and developed at our institute. Fit-for-purpose pharmacokinetic properties is urgently needed to be… read more here.

Keywords: ipa08 bioavailability; bioavailability; pass effect; ipa08 ... See more keywords