Recombinant Expression and Purification of the Shigella Translocator IpaB.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6649-3_15
Abstract: Type III secretion systems (T3SS) are highly conserved virulence factors employed by a large number of pathogenic gram-negative bacteria. Like many T3SS translocators, recombinant expression of the hydrophobic Shigella protein IpaB requires the presence of… read more here.
Keywords: shigella; expression; ipab; expression purification ... See more keywords
In silico design of a novel chimeric shigella IpaB fused to C terminal of clostridium perfringens enterotoxin as a vaccine candidate
Sign Up to like & getrecommendations! Published in 2018 at "Bioengineered"
DOI: 10.1080/21655979.2017.1373535
Abstract: ABSTRACT This study aimed to design a novel chimeric protein in silico to serve as a serotype-independent vaccine candidate against Shigella. The chimera contains amino acid residues 240–460 of Shigella invasion plasmid antigen B (IpaB)… read more here.
Keywords: cpe194 319; vaccine candidate; cpe290 319; shigella ... See more keywords
Characterization of Functional B-Cell Epitopes at the Amino Terminus of Shigella Invasion Plasmid Antigen B (IpaB)
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DOI: 10.1128/aem.00384-22
Abstract: Currently, there are no effective measures for control or prevention of Shigella infection, the most common cause of diarrhea in children 3 to 5 years of age in developing countries. Challenges in developing Shigella vaccines… read more here.
Keywords: ipab; shigella; invasion plasmid; antigen ... See more keywords
A Novel Shigella O-Polysaccharide–IpaB Conjugate Vaccine Elicits Robust Antibody Responses and Confers Protection against Multiple Shigella Serotypes
Sign Up to like & getrecommendations! Published in 2023 at "mSphere"
DOI: 10.1128/msphere.00019-23
Abstract: Diarrhea caused by Shigella species results in long-term disability and mortality globally, disproportionally affecting younger children living in poor countries. Although it is treatable by antibiotics, the rapid and widespread emergence of resistant strains and… read more here.
Keywords: ipab; conjugate vaccine; shigella; novel shigella ... See more keywords