Articles with "ipec" as a keyword



Protective effect of crocin on peroxidation‐induced oxidative stress and apoptosis in IPEC‐J2 cells

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Published in 2024 at "Environmental Toxicology"

DOI: 10.1002/tox.24216

Abstract: The antioxidant properties of crocin are attracting interest, yet the underlying mechanisms by which crocin mitigates oxidative stress‐induced intestinal damage have not been determined. This study aimed to elucidate the effects of crocin on oxidative… read more here.

Keywords: crocin; stress; oxidative stress; induced oxidative ... See more keywords

Ochratoxin A-Induced Apoptosis of IPEC-J2 Cells through ROS-Mediated Mitochondrial Permeability Transition Pore Opening Pathway.

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Published in 2017 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.7b04434

Abstract: With the purpose to explore the mechanisms associated with the intestinal toxicity of Ochratoxin A (OTA), an intestinal porcine epithelial cell line (IPEC-J2) was applied in this study as in vitro models for intestinal epithelium.… read more here.

Keywords: apoptosis; ipec; mitochondrial permeability; ota induced ... See more keywords

Air–liquid interface enhances oxidative phosphorylation in intestinal epithelial cell line IPEC-J2

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Published in 2017 at "Cell Death Discovery"

DOI: 10.1038/cddiscovery.2017.1

Abstract: The intestinal porcine epithelial cell line IPEC-J2, cultured under the air–liquid interface (ALI) conditions, develops remarkable morphological characteristics close to intestinal epithelial cells in vivo. Improved oxygen availability has been hypothesised to be the leading… read more here.

Keywords: ipec; ali; interface; cell ... See more keywords

Patient-described factors impacting the ability to implement and adhere to lifestyle change: findings from the patient-led Insights from Patients living with Elevated Cholesterol (IPEC) study

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Published in 2025 at "European Journal of Preventive Cardiology"

DOI: 10.1093/eurjpc/zwaf236.488

Abstract: Lifestyle changes such as adopting a heart-healthy diet, increasing physical activity, and maintaining a healthy weight are critical interventions for managing cholesterol levels. However, many individuals face significant barriers to implementing these changes. The objective… read more here.

Keywords: lifestyle changes; family; make lifestyle; ability ... See more keywords

Mitigative effects of Eleutheroside E against the mechanical barrier dysfunction induced by soybean agglutinin in IPEC-J2 cell line.

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Published in 2022 at "Journal of animal physiology and animal nutrition"

DOI: 10.1111/jpn.13677

Abstract: Soybean agglutinin (SBA) is an anti-nutritional factor which decreases the mechanical barrier function in intestinal porcine jejunum epithelial cells (IPEC-J2). Eleutheroside E (EE) is a key part of Acanthopanax senticosus to exert pharmacological effects. This… read more here.

Keywords: soybean agglutinin; barrier dysfunction; barrier function; barrier ... See more keywords

Transport of glycinin, the major soybean allergen, across intestinal epithelial IPEC-J2 cell monolayers.

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Published in 2024 at "Journal of animal physiology and animal nutrition"

DOI: 10.1111/jpn.13975

Abstract: Soybean allergen entering the body is the initial step to trigger intestinal allergic response. However, it remains unclear how glycinin, the major soybean allergen, is transported through the intestinal mucosal barrier. The objective of this… read more here.

Keywords: soybean; ipec; glycinin; ipec cell ... See more keywords

The Inflammatory Response to Enterotoxigenic E. coli and Probiotic E. faecium in a Coculture Model of Porcine Intestinal Epithelial and Dendritic Cells

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Published in 2018 at "Mediators of Inflammation"

DOI: 10.1155/2018/9368295

Abstract: The gut epithelium constitutes an interface between the intestinal contents and the underlying gut-associated lymphoid tissue (GALT) including dendritic cells (DC). Interactions of intestinal epithelial cells (IEC) and resident DC are characterized by bidirectional crosstalk… read more here.

Keywords: intestinal epithelial; ipec; ipec cells; model ... See more keywords

The protective effect of Eleutheroside E against the mechanical barrier dysfunction triggered by lipopolysaccharide in IPEC-J2 cells.

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Published in 2022 at "Research in veterinary science"

DOI: 10.2139/ssrn.4166588

Abstract: Eleutheroside E (EE) exhibits immunocompetence, antioxidant, and anti-inflammatory activity. Lipopolysaccharide (LPS) can elicit a strong immune response. In vitro experiments were used to explore whether EE protects intestinal porcine jejunum epithelial cells (IPEC-J2) barriers from… read more here.

Keywords: effect; ipec; expression; group ... See more keywords

Effects of stearic acid on proliferation, differentiation, apoptosis, and autophagy in porcine intestinal epithelial cells.

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Published in 2019 at "Current molecular medicine"

DOI: 10.2174/1566524019666190917144127

Abstract: Stearic acid (SA), a saturated long-chain fatty acid consisting of 18 carbon atoms, is widely found in feed ingredients such as corn, soybeans, and wheat. However, the roles of SA in the renewal of intestinal… read more here.

Keywords: epithelial cells; intestinal epithelial; apoptosis; ipec ... See more keywords

Effects of 1,2-Dimethylhydrazine on Barrier Properties of Rat Large Intestine and IPEC-J2 Cells

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms221910278

Abstract: Colon cancer is accompanied by a decrease of epithelial barrier properties, which are determined by tight junction (TJ) proteins between adjacent epithelial cells. The aim of the current study was to analyze the expression of… read more here.

Keywords: ipec; ipec cells; effects dimethylhydrazine; expression ... See more keywords

Baicalin Attenuates H2O2-Induced Oxidative Stress by Regulating the AMPK/Nrf2 Signaling Pathway in IPEC-J2 Cells

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24119435

Abstract: Oxidative stress can adversely affect the health status of the body, more specifically by causing intestinal damage by disrupting the permeability of the intestinal barrier. This is closely related to intestinal epithelial cell apoptosis caused… read more here.

Keywords: h2o2 induced; ipec; oxidative stress; ipec cells ... See more keywords