Ochratoxin A-Induced Apoptosis of IPEC-J2 Cells through ROS-Mediated Mitochondrial Permeability Transition Pore Opening Pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.7b04434
Abstract: With the purpose to explore the mechanisms associated with the intestinal toxicity of Ochratoxin A (OTA), an intestinal porcine epithelial cell line (IPEC-J2) was applied in this study as in vitro models for intestinal epithelium.… read more here.
Keywords: apoptosis; ipec; mitochondrial permeability; ota induced ... See more keywords
Air–liquid interface enhances oxidative phosphorylation in intestinal epithelial cell line IPEC-J2
Sign Up to like & getrecommendations! Published in 2017 at "Cell Death Discovery"
DOI: 10.1038/cddiscovery.2017.1
Abstract: The intestinal porcine epithelial cell line IPEC-J2, cultured under the air–liquid interface (ALI) conditions, develops remarkable morphological characteristics close to intestinal epithelial cells in vivo. Improved oxygen availability has been hypothesised to be the leading… read more here.
Keywords: ipec; ali; interface; cell ... See more keywords
Mitigative effects of Eleutheroside E against the mechanical barrier dysfunction induced by soybean agglutinin in IPEC-J2 cell line.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of animal physiology and animal nutrition"
DOI: 10.1111/jpn.13677
Abstract: Soybean agglutinin (SBA) is an anti-nutritional factor which decreases the mechanical barrier function in intestinal porcine jejunum epithelial cells (IPEC-J2). Eleutheroside E (EE) is a key part of Acanthopanax senticosus to exert pharmacological effects. This… read more here.
Keywords: soybean agglutinin; barrier dysfunction; barrier function; barrier ... See more keywords
The Inflammatory Response to Enterotoxigenic E. coli and Probiotic E. faecium in a Coculture Model of Porcine Intestinal Epithelial and Dendritic Cells
Sign Up to like & getrecommendations! Published in 2018 at "Mediators of Inflammation"
DOI: 10.1155/2018/9368295
Abstract: The gut epithelium constitutes an interface between the intestinal contents and the underlying gut-associated lymphoid tissue (GALT) including dendritic cells (DC). Interactions of intestinal epithelial cells (IEC) and resident DC are characterized by bidirectional crosstalk… read more here.
Keywords: intestinal epithelial; ipec; ipec cells; model ... See more keywords
The protective effect of Eleutheroside E against the mechanical barrier dysfunction triggered by lipopolysaccharide in IPEC-J2 cells.
Sign Up to like & getrecommendations! Published in 2022 at "Research in veterinary science"
DOI: 10.2139/ssrn.4166588
Abstract: Eleutheroside E (EE) exhibits immunocompetence, antioxidant, and anti-inflammatory activity. Lipopolysaccharide (LPS) can elicit a strong immune response. In vitro experiments were used to explore whether EE protects intestinal porcine jejunum epithelial cells (IPEC-J2) barriers from… read more here.
Keywords: effect; ipec; expression; group ... See more keywords
Effects of stearic acid on proliferation, differentiation, apoptosis, and autophagy in porcine intestinal epithelial cells.
Sign Up to like & getrecommendations! Published in 2019 at "Current molecular medicine"
DOI: 10.2174/1566524019666190917144127
Abstract: Stearic acid (SA), a saturated long-chain fatty acid consisting of 18 carbon atoms, is widely found in feed ingredients such as corn, soybeans, and wheat. However, the roles of SA in the renewal of intestinal… read more here.
Keywords: epithelial cells; intestinal epithelial; apoptosis; ipec ... See more keywords
Effects of 1,2-Dimethylhydrazine on Barrier Properties of Rat Large Intestine and IPEC-J2 Cells
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms221910278
Abstract: Colon cancer is accompanied by a decrease of epithelial barrier properties, which are determined by tight junction (TJ) proteins between adjacent epithelial cells. The aim of the current study was to analyze the expression of… read more here.
Keywords: ipec; ipec cells; effects dimethylhydrazine; expression ... See more keywords
Baicalin Attenuates H2O2-Induced Oxidative Stress by Regulating the AMPK/Nrf2 Signaling Pathway in IPEC-J2 Cells
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119435
Abstract: Oxidative stress can adversely affect the health status of the body, more specifically by causing intestinal damage by disrupting the permeability of the intestinal barrier. This is closely related to intestinal epithelial cell apoptosis caused… read more here.
Keywords: h2o2 induced; ipec; oxidative stress; ipec cells ... See more keywords
Low-Molecular-Weight Chitosan Attenuates Lipopolysaccharide-Induced Inflammation in IPEC-J2 Cells by Inhibiting the Nuclear Factor-κB Signalling Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26030569
Abstract: Low-molecular-weight chitosan (LMWC), a product of chitosan deacetylation, possesses anti-inflammatory effects. In the present study, a porcine small intestinal epithelial cell line, IPEC-J2, was used to assess the protective effects of LMWC on lipopolysaccharide (LPS)-induced… read more here.
Keywords: low molecular; weight chitosan; ipec; ipec cells ... See more keywords
Astaxanthin Alleviates Aflatoxin B1-Induced Oxidative Stress and Apoptosis in IPEC-J2 Cells via the Nrf2 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2023 at "Toxins"
DOI: 10.3390/toxins15030232
Abstract: Aflatoxin B1 (AFB1), a typical fungal toxin found in feed, is highly carcinogenic. Oxidative stress is one of the main ways it exerts its toxicity; therefore, finding a suitable antioxidant is the key to reducing… read more here.
Keywords: signaling pathway; ipec; oxidative stress; nrf2 signaling ... See more keywords