Articles with "ipec cells" as a keyword



Glyphosate‐based herbicides induces autophagy in IPEC‐J2 cells and the intervention of N‐acetylcysteine

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Published in 2022 at "Environmental Toxicology"

DOI: 10.1002/tox.23534

Abstract: Glyphosate‐based herbicides (GBHs) are the most widely used pesticide in the world, and its extensive use has increased pressures on environmental safety and potential human and livestock health risks. This study investigated the effects of… read more here.

Keywords: glyphosate based; based herbicides; ipec cells; regulation ... See more keywords

MicroRNA-21-5p targets PDCD4 to modulate apoptosis and inflammatory response to Clostridium perfringens beta2 toxin infection in IPEC-J2 cells.

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Published in 2020 at "Developmental and comparative immunology"

DOI: 10.1016/j.dci.2020.103849

Abstract: Clostridium perfringens (C. perfringens), a toxin-producing enteric pathogen, causes a variety of intestinal infections in humans and animals. C. perfringens beta2 (CPB2) toxin has been considered to be a strong virulence factor for C. perfringens… read more here.

Keywords: response; apoptosis; clostridium perfringens; ipec cells ... See more keywords

Proteomic analysis reveals the molecular mechanism of Hippophae rhamnoides polysaccharide intervention in LPS-induced inflammation of IPEC-J2 cells in piglets.

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Published in 2020 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2020.08.235

Abstract: Early weaning can cause intestinal disorders and dysfunction in piglets, and may induce intestinal diseases. Hippophae rhamnoides polysaccharide (HRP) has anti-inflammatory and immune promotion function. However, few studies have explored the change of differentially protein… read more here.

Keywords: lps induced; hippophae rhamnoides; analysis; ipec cells ... See more keywords

Chemical composition and anti-inflammatory activity of n-butanol extract of Piper sarmentosum Roxb. in the intestinal porcine epithelial cells (IPEC-J2).

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Published in 2020 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2020.113723

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Piper sarmentosum Roxb. (PS) is a terrestrial herb primarily distributed in tropical and subtropical regions of Asia. It is widely used in folk medicine in certain countries of Southeast Asia for the treatment… read more here.

Keywords: anti inflammatory; butanol extract; ipec cells; inflammatory activity ... See more keywords

4-Phenylbutyric Acid Attenuates Soybean Glycinin/β-Conglycinin-Induced IPEC-J2 Cells Apoptosis by Regulating the Mitochondria-Associated Endoplasmic Reticulum Membrane and NLRP-3.

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Published in 2024 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.3c09630

Abstract: Glycinin (11S) and β-conglycinin (7S) from soybean (glycine max) cause diarrhea and intestinal barrier damage in young animals. Understanding the mechanisms underlying the damage caused by 7S and 11S, it is vital to develop strategies… read more here.

Keywords: phenylbutyric acid; ipec cells; endoplasmic reticulum; mitochondria associated ... See more keywords

miRNA Expression Analysis of IPEC-J2 Cells Damaged by Soybean 7S Globulin Reveals ssc-miR-221-5p as the Factor Alleviating Cell Damage.

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Published in 2024 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.4c02047

Abstract: The most significant and sensitive antigen protein that causes diarrhea in weaned pigs is soybean 7S globulin. Therefore, identifying the primary target for minimizing intestinal damage brought on by soybean 7S globulin is crucial. MicroRNA… read more here.

Keywords: mir 221; soybean globulin; ssc mir; ipec cells ... See more keywords

PSVIII-1 Nutrient starvation induces autophagy and alters intestinal barrier function in IPEC-J2 cells

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Published in 2019 at "Journal of Animal Science"

DOI: 10.1093/jas/skz258.575

Abstract: Autophagy is a cellular process of controlled degradation of damaged organelles and cytoplasmic macromolecules during stress for maintaining homeostasis. Intestinal epithelial cells are barriers against microorganisms, toxins and food antigens. Whether autophagy plays a role… read more here.

Keywords: starvation; claudin; intestinal barrier; ipec cells ... See more keywords

Protective Effects of Methylsulfonylmethane (MSM) on Barrier Function Injury of Porcine Intestinal Epithelial (IPEC-J2) Cells Induced by Lipopolysaccharide (LPS)

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Published in 2023 at "Canadian Journal of Animal Science"

DOI: 10.1139/cjas-2022-0141

Abstract: Methylsulfonylmethane (MSM) is a natural organic sulfur component, which has anti-inflammatory and antioxidant properties. In this study, IPEC-J2 cells model were used to investigate the effect of MSM on lipopolysaccharide (LPS)-induced porcine intestinal epithelium barrier… read more here.

Keywords: porcine intestinal; msm; methylsulfonylmethane msm; protective effects ... See more keywords

The Inflammatory Response to Enterotoxigenic E. coli and Probiotic E. faecium in a Coculture Model of Porcine Intestinal Epithelial and Dendritic Cells

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Published in 2018 at "Mediators of Inflammation"

DOI: 10.1155/2018/9368295

Abstract: The gut epithelium constitutes an interface between the intestinal contents and the underlying gut-associated lymphoid tissue (GALT) including dendritic cells (DC). Interactions of intestinal epithelial cells (IEC) and resident DC are characterized by bidirectional crosstalk… read more here.

Keywords: intestinal epithelial; ipec; ipec cells; model ... See more keywords

circGLI3 Inhibits Oxidative Stress by Regulating the miR-339-5p/VEGFA Axis in IPEC-J2 Cells

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Published in 2021 at "BioMed Research International"

DOI: 10.1155/2021/1086206

Abstract: As a new type of noncoding RNA, circular RNA (circRNA) is stable in cells and not easily degraded. This type of RNA can also competitively bind miRNAs to regulate the expression of their target genes.… read more here.

Keywords: ipec cells; mir 339; circgli3; vegfa ... See more keywords

Porcine beta defensin 2 attenuates inflammatory responses in IPEC-J2 cells against Escherichia coli via TLRs-NF-κB/MAPK signaling pathway

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Published in 2024 at "BMC Veterinary Research"

DOI: 10.1186/s12917-024-04220-7

Abstract: Background Porcine beta defensin 2 (pBD2) is one of the porcine beta defensins that has antibacterial activity, and plays an important role in the immunomodulatory activity that protects cells from pathogens. It has been reported… read more here.

Keywords: ipec cells; porcine beta; pbd2; beta defensin ... See more keywords