Ipilimumab treatment associated with myasthenic crises and unfavorable disease course
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DOI: 10.1007/s10072-018-3471-6
Abstract: Ipilimumab, a monoclonal antibody targeting the cytotoxic T lymphocyte antigen-4 is a treatment option for metastatic melanoma. This receptor serves as an inhibitor receptor on T lymphocytes and blockage of these results predisposition to autoimmune… read more here.
Keywords: treatment associated; crises unfavorable; treatment; myasthenic crises ... See more keywords
Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in long-term survivors with advanced melanoma
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DOI: 10.18632/oncotarget.15368
Abstract: Ipilimumab has revolutionized malignant melanoma therapy, but a better understanding of the mechanisms behind treatment response and adverse effects is needed. In this work, the immune system of ipilimumab treated patients was monitored to investigate… read more here.
Keywords: advanced melanoma; treatment; cd8 effector; monocytic mdscs ... See more keywords