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   Articles with "ipla2" as a keyword



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Phospholipase iPLA2γ participates in cellular antioxidant and anti-inflammatory protection in vivo

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recommendations! Published in 2017 at "Free Radical Biology and Medicine"

DOI: 10.1016/j.freeradbiomed.2017.10.024

Abstract: The mitochondrial Ca2+-independent phospholipase A2γ (iPLA2γ) plays an antioxidant role in various tissues.1 iPLA2γ is redox-dependent, releasing free fatty acids as substrates for mitochondrial uncoupling protein 2 and possibly other SLC25 family carriers, resulting in… read more here.

Keywords: ipla2; anti inflammatory; antioxidant anti; phospholipase ipla2 ... See more keywords
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Chlorine dioxide enhances lipid peroxidation through inhibiting calcium-independent cellular PLA2 in larvae of the Indianmeal moth, Plodia interpunctella.

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recommendations! Published in 2017 at "Pesticide biochemistry and physiology"

DOI: 10.1016/j.pestbp.2017.09.010

Abstract: Polyunsaturated fatty acids usually undergo lipid peroxidation induced by reactive oxygen species (ROS). Calcium-independent cellular phospholipase A2 (iPLA2) can maintain fatty acid compositions in phospholipids depending on physiological conditions. An insect iPLA2 (Pi-iPLA2) was predicted… read more here.

Keywords: ipla2; indianmeal moth; lipid peroxidation; peroxidation ... See more keywords
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iPLA2β Contributes to Activation of Human and Mouse Platelets Via ITAM Receptors Fcγ RIIA and GPVI

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recommendations! Published in 2019 at "Blood"

DOI: 10.1182/blood-2019-128426

Abstract: Platelet activation by ITAM receptors contributes to hemostasis, thrombosis, vascular integrity and host defense. In the course of our studies of FcγRIIA-mediated platelet activation, we became interested in those mechanisms that require neither full Syk… read more here.

Keywords: ipla2; mouse platelets; human riia; activation ... See more keywords
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Antioxidant Role and Cardiolipin Remodeling by Redox-Activated Mitochondrial Ca2+-Independent Phospholipase A2γ in the Brain

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recommendations! Published in 2022 at "Antioxidants"

DOI: 10.3390/antiox11020198

Abstract: Mitochondrial Ca2+-independent phospholipase A2γ (iPLA2γ/PNPLA8) was previously shown to be directly activated by H2O2 and release free fatty acids (FAs) for FA-dependent H+ transport mediated by the adenine nucleotide translocase (ANT) or uncoupling protein 2… read more here.

Keywords: antioxidant role; brain; ca2 independent; ipla2 ... See more keywords