Abstract 853: GPX4 Gene Expression is Dose-responsive to Doxorubicin Exposure in iPSC-Cardiomyocytes and Correlated With Mitochondrial Function
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/res.125.suppl_1.853
Abstract: Impaired mitochondrial function has been implicated as a mechanism of doxorubicin-induced cardiotoxicity, however the precise genes that regulate this process in human cardiomyocytes remain to be elucidated. We hypothesized that doxorubicin significantly alters expression of… read more here.
Keywords: ipsc cardiomyocytes; mitochondrial function; gene expression; expression ... See more keywords
The Structural and the Functional Aspects of Intercellular Communication in iPSC-Cardiomyocytes
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DOI: 10.3390/ijms23084460
Abstract: Recent advances in the technology of producing novel cardiomyocytes from induced pluripotent stem cells (iPSC-cardiomyocytes) fuel new hope for future clinical applications. The use of iPSC-cardiomyocytes is particularly promising for the therapy of cardiac diseases… read more here.
Keywords: ipsc cardiomyocytes; functional aspects; communication; ipsc ... See more keywords