Patient-Specific iPSC Model of a Genetic Vascular Dementia Syndrome Reveals Failure of Mural Cells to Stabilize Capillary Structures
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DOI: 10.1016/j.stemcr.2019.10.004
Abstract: Summary CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is the most common form of genetic stroke and vascular dementia syndrome resulting from mutations in NOTCH3. To elucidate molecular mechanisms of the condition… read more here.
Keywords: patient specific; vascular dementia; dementia; ipsc model ... See more keywords