iPSC-RPE in Retinal Degeneration: Recent Advancements and Future Perspectives.
Sign Up to like & getrecommendations! Published in 2023 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a041308
Abstract: Regenerative medicine is a great hope for patients suffering from diseases for which no effective treatment is available. With the creation of induced pluripotent stem cells (iPSCs) in 2006, research and development has accelerated expeditiously,… read more here.
Keywords: retinal degeneration; regenerative medicine; rpe retinal; ipsc rpe ... See more keywords
[Experimental stem cell replacement transplantation in retinal pigment epithelium atrophy].
Sign Up to like & getrecommendations! Published in 2022 at "Vestnik oftalmologii"
DOI: 10.17116/oftalma20221380317
Abstract: PURPOSE To develop and evaluate the results of the modified surgical technique for transplantation of retinal pigment epithelium (RPE) differentiated from human induced pluripotent stem cells (iPSC-RPE) in the form of a cell suspension into… read more here.
Keywords: cell; rpe; transplantation; atrophy ... See more keywords
Induced Pluripotent Stem Cell Modeling of Best Disease and Autosomal Recessive Bestrophinopathy
Sign Up to like & getrecommendations! Published in 2020 at "Yonsei Medical Journal"
DOI: 10.3349/ymj.2020.61.9.816
Abstract: Purpose To understand the pathophysiology of Best disease (BD) and autosomal recessive bestrophinopathy (ARB) by establishing an in vitro model using human induced pluripotent stem cell (iPSC). Materials and Methods Human iPSC lines were generated… read more here.
Keywords: ipsc rpe; disease autosomal; ipsc; best disease ... See more keywords
Transcriptional comparison of adult human primary Retinal Pigment Epithelium, human pluripotent stem cell-derived Retinal Pigment Epithelium, and ARPE19 cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.910040
Abstract: The therapeutic potential of pluripotent stem cells is great as they promise to usher in a new era of medicine where cells or organs may be prescribed to replace dysfunctional tissue. At the forefront are… read more here.
Keywords: rpe; retinal pigment; pigment epithelium; ipsc rpe ... See more keywords
Human iPSC- and Primary-Retinal Pigment Epithelial Cells for Modeling Age-Related Macular Degeneration
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11040605
Abstract: Primary cultures of retinal pigment epithelium (RPE) from human adult donors (haRPE) and induced pluripotent stem cell derived-RPE (iPSC-RPE) are valuable model systems for gaining mechanistic insight and for testing potential therapies for age-related macular… read more here.
Keywords: response; ipsc rpe; treatment; retinal pigment ... See more keywords