Genomic Instability of iPSCs and Challenges in Their Clinical Applications.
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DOI: 10.1007/978-3-030-31206-0_2
Abstract: Generation of human-induced pluripotent stem cells (iPSCs) from somatic cells has opened the possibility to design novel therapeutic approaches. In 2014, the first-in-human clinical trial of iPSC-based therapy was conducted. However, the transplantation for the… read more here.
Keywords: ipscs challenges; genetic aberrations; genomic instability; instability ipscs ... See more keywords