The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase.
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DOI: 10.1073/pnas.2302584120
Abstract: Mutations in the TMEM260 gene cause structural heart defects and renal anomalies syndrome, but the function of the encoded protein remains unknown. We previously reported wide occurrence of O-mannose glycans on extracellular immunoglobulin, plexin, transcription… read more here.
Keywords: ipt domains; protein specific; mannosyltransferase; gene ... See more keywords