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Nonhematopoietic IRAK1 drives arthritis via neutrophil chemoattractants

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Published in 2022 at "JCI Insight"

DOI: 10.1172/jci.insight.149825

Abstract: IL-1 receptor-activated kinase 1 (IRAK1) is involved in signal transduction downstream of many TLRs and the IL-1R. Its potential as a drug target for chronic inflammatory diseases is underappreciated. To study its functional role in… read more here.

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