A crosstalk between hepcidin and IRE/IRP pathways controls ferroportin expression and determines serum iron levels in mice
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2021.10.29.466457
Abstract: The iron hormone hepcidin is transcriptionally activated by iron or inflammation via distinct, partially overlapping pathways. We addressed how iron affects inflammatory hepcidin levels and the ensuing hypoferremic response. Dietary iron overload did not mitigate… read more here.
Keywords: serum iron; iron; ire irp; hepcidin ... See more keywords