Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation
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DOI: 10.1186/s13073-018-0589-3
Abstract: BackgroundThe IRE1a-XBP1 pathway is a conserved adaptive mediator of the unfolded protein response. The pathway is indispensable for the development of secretory cells by facilitating protein folding and enhancing secretory capacity. In the immune system,… read more here.
Keywords: xbp1 pathway; helper cell; ire1a xbp1; xbp1 ... See more keywords