A rapid method for solubilization of chimeric human interferon regulatory factor-1 (IRF-1) protein in Escherichia coli.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06260-w
Abstract: Interferon regulatory factor-1 (IRF-1) is a vertebrate transcription factor that plays significant roles in cell cycle regulation, anti-viral response, tumor suppression and immune response. High-level expression of recombinant IRF-1 at 37 °C leads to the formation… read more here.
Keywords: irf; interferon regulatory; factor irf; regulatory factor ... See more keywords
IRF-5 Promotes Cell Death in CD4 T Cells during Chronic Infection.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.06.107
Abstract: The transcription factor interferon regulatory factor 5 (IRF-5) plays an important function in innate immunity and in initiating pro-inflammatory responses against pathogens. IRF-5 is constitutively expressed in several cell types, including plasmacytoid dendritic cells, monocytes,… read more here.
Keywords: cd4 cells; infection; irf; cell death ... See more keywords
The antineoplastic drug metformin downregulates YAP by interfering with IRF-1 binding to the YAP promoter in NSCLC
Sign Up to like & getrecommendations! Published in 2018 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2018.10.044
Abstract: Background Activation of the oncogene YAP has been shown to be related to lung cancer progression and associates with poor prognosis and metastasis. Metformin is a drug commonly used in the treatment of diabetes and… read more here.
Keywords: yap promoter; irf; lung cancer;
Contribution of phases segregated from the UO2 matrix to the release of radionuclides from spent nuclear fuel and duration of the Instant Release Fraction (IRF)
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Nuclear Materials"
DOI: 10.1016/j.jnucmat.2020.152066
Abstract: Abstract During the dissolution of the spent nuclear fuel (SNF) some radionuclides are released to the solution simultaneously from different sources in the fuel. This is of particular importance to some radionuclides that contribute to… read more here.
Keywords: irf; contribution; fuel; dissolution ... See more keywords
Ginsenoside (Rg-1) promoted the wound closure of diabetic foot ulcer through iNOS elevation via miR-23a/IRF-1 axis.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.05.081
Abstract: BACKGROUND Impaired wound healing in diabetes foot ulcers (DFUs) brings a great burden to diabetic patients. Pro-angiogenesis through elevating nitric oxide (NO) is beneficial to the wound healing process. Ginsenoside Rg1, the main active in… read more here.
Keywords: mir 23a; irf; rg1; wound closure ... See more keywords
Clinical utility of immature reticulocyte fraction for identifying early red blood cell regeneration in anemic dogs
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Veterinary Internal Medicine"
DOI: 10.1111/jvim.16641
Abstract: Abstract Background Evaluating regeneration is essential for the classification and differential diagnosis of anemia in dogs. Early detection of regeneration is challenging in anemic dogs. Objectives This study assessed the value of immature reticulocyte fraction… read more here.
Keywords: regeneration; regeneration anemic; anemic dogs; immature reticulocyte ... See more keywords
Interferon Regulatory Factor 7 Attenuates Chronic Gammaherpesvirus Infection
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Virology"
DOI: 10.1128/jvi.01554-20
Abstract: The innate immune system of the host is critical for the restriction of acute viral infections. In contrast, the role of the innate immune network during chronic herpesvirus infection remains poorly defined. Interferon regulatory factor… read more here.
Keywords: role irf; infection; factor; gammaherpesvirus ... See more keywords
Tissue methylation and demethylation influence translesion synthesis DNA polymerases (TLS) contributing to the genesis of chromosomal abnormalities in myelodysplastic syndrome
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2020-207131
Abstract: Aims DNA methylation has its distribution influenced by DNA demethylation processes with the catalytic conversion of 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC). Myelodysplastic syndrome (MDS) has been associated with epigenetic dysregulation of genes related to DNA… read more here.
Keywords: methylation; irf; dna; translesion ... See more keywords
The Immature Reticulocyte Fraction As an Aid in the Diagnosis and Prognosis of Parvovirus B19 Infection in Sickle Cell Disease
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DOI: 10.1182/blood-2018-99-117152
Abstract: Background Sickle cell disease (SCD) is characterized by hemoglobin polymerization leading to vaso-occlusion, chronic hemolysis and vasculopathy. Parvovirus B19 (B19) infection causes an acute arrest of erythropoiesis leading to reticulocytopenia and potentially life-threatening anemia in… read more here.
Keywords: irf; b19 infection; infection; reticulocyte ... See more keywords
IRF-2 inhibits cancer proliferation by promoting AMER-1 transcription in human gastric cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-022-03275-0
Abstract: Background Interferon regulatory factor 2 (IRF-2) acts as an anti-oncogene in gastric cancer (GC); however, the underlying mechanism remains unknown. Methods This study determined the expression of IRF-2 in GC tissues and adjacent non-tumor tissues… read more here.
Keywords: cancer; tumor; irf; proliferation ... See more keywords
Renal outcomes of suprarenal vs. infrarenal endograft fixation in endovascular abdominal aortic aneurysm repair: a narrative review
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular Diagnosis and Therapy"
DOI: 10.21037/cdt-22-196
Abstract: Background and Objective Abdominal aortic aneurysm (AAA) is a common pathology with a prevalence of 4.8%. AAA rupture is associated with significant mortality and so early diagnosis followed by regular monitoring is needed until treatment… read more here.
Keywords: endograft; renal outcomes; irf; aneurysm ... See more keywords