Pristane induces autophagy in macrophages, promoting a STAT1-IRF1-TLR3 pathway and arthritis.
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DOI: 10.1016/j.clim.2016.11.017
Abstract: Autophagy is involved in both innate and adaptive immune regulation. We propose that autophagy regulates activation of TLR3 in macrophages and is thereby essential for development of pristane-induced arthritis. We found that pristane treatment induced… read more here.
Keywords: stat1 irf1; pristane; irf1 tlr3; tlr3 ... See more keywords