TLR3 preconditioning induces anti-inflammatory and anti-ictogenic effects in mice mediated by the IRF3/IFN-β axis
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DOI: 10.1016/j.bbi.2019.07.021
Abstract: Activation of Toll-like receptor 3 (TLR3) was previously shown to contribute to the generation of epileptic seizures in rodents by evoking a proinflammatory response in the forebrain. This suggests that TLR3 blockade may provide therapeutic… read more here.
Keywords: tlr3; ifn; irf3 ifn; ifn axis ... See more keywords