Specific enhancer selection by IRF3, IRF5 and IRF9 is determined by ISRE half-sites, 5′ and 3′ flanking bases, collaborating transcription factors and the chromatin environment in a combinatorial fashion
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DOI: 10.1093/nar/gkz1112
Abstract: Abstract IRF3, IRF5 and IRF9 are transcription factors, which play distinct roles in the regulation of antiviral and inflammatory responses. The determinants that mediate IRF-specific enhancer selection are not fully understood. To uncover regions occupied… read more here.
Keywords: irf3 irf5; irf5 irf9; isre half; irf9 ... See more keywords