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IRF4b and IRF8 Negatively Regulate RLR-Mediated NF-κB Signaling by Targeting MITA for Degradation in Teleost Fish

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.858179

Abstract: Mediator of IRF3 activation (MITA) is a significant signal adaptor in the retinoic acid-inducible gene-I like receptor (RLR) signaling pathway and plays an important role in the innate immune system. As a transcription factor, nuclear… read more here.

Keywords: signaling pathway; rlr; mediated signaling; irf4b irf8 ... See more keywords