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Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30559
Abstract: Nonalcoholic fatty liver disease (NAFLD) has become a worldwide epidemic. A large and growing unmet therapeutic need has inspired numerous studies in the field. Integrating the published genomic data available in the Gene Expression Omnibus…
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Keywords:
interferon regulatory;
regulatory factor;
irf6;
mice ... See more keywords
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Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.1c02722
Abstract: The following salts have been synthesized and structurally characterized: Na2[IrF6]·2H2O (C2/m, a = 6.6327(4), b = 10.0740(6), c = 5.9283(5) Å, β = 122.3880(10)°) and Na3[IrF6]·2H2O (R-3, a = 7.5963(3), b = 7.5963(3), c =…
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Keywords:
sodium hexafluoroiridates;
revisiting sodium;
hexafluoroiridates perspective;
irf6 ... See more keywords
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Published in 2018 at "Nature Genetics"
DOI: 10.1038/s41588-018-0168-y
Abstract: Multiple sclerosis (MS) is a disease of the central nervous system treated with disease-modifying therapies, including the biologic, interferon-β (IFN-β). Up to 60% of IFN-β-exposed MS patients develop abnormal biochemical liver test results1,2, and 1…
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Keywords:
liver injury;
ifn;
multiple sclerosis;
irf6 ... See more keywords
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Published in 2020 at "Oral diseases"
DOI: 10.1111/odi.13403
Abstract: We present here the first reported case of a non-syndromic cleft lip and palate (NSCLP) in an HIV-exposed newborn of a mother on antiretroviral therapy (ART) in Indonesia. Genetic testing was performed to confirm a…
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Keywords:
syndromic cleft;
lip palate;
non syndromic;
irf6 ... See more keywords
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Published in 2017 at "Journal of Dental Research"
DOI: 10.1177/0022034517719870
Abstract: Rare mutations in IRF6 and GRHL3 cause Van der Woude syndrome, an autosomal dominant orofacial clefting disorder. Common variants in IRF6 and GRHL3 also contribute risk for isolated orofacial clefting. Similarly, variants within genes that…
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Keywords:
irf6 spry4;
signaling interact;
abnormal oral;
irf6 ... See more keywords
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Published in 2023 at "Cancers"
DOI: 10.3390/cancers15030737
Abstract: Simple Summary The aim of our study is to understand the signaling mechanisms behind the tumor suppressive function of RIPK4 (receptor-interacting serine/threonine protein kinase 4) in squamous cell carcinomas (SCCs) of skin, head, and neck…
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Keywords:
ripk4 irf6;
squamous cell;
ripk4;
irf6 ... See more keywords