Novel IRF6 mutations in Chinese Han families with Van der Woude syndrome
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1196
Abstract: Interferon Regulatory Factor 6 (IRF6) gene encodes a member of the IRF family of transcription factors. Mutations in IRF6 cause Van der Woude Syndrome (VWS), which is the most common malformation of syndromic orofacial clefts… read more here.
Keywords: van der; der woude; novel irf6; mutations chinese ... See more keywords
Novel IRF6 Mutations Detected in Orofacial Cleft Patients by Targeted Massively Parallel Sequencing
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Dental Research"
DOI: 10.1177/0022034516678829
Abstract: Common variants in interferon regulatory factor 6 (IRF6) have been associated with nonsyndromic cleft lip with or without cleft palate (NSCL/P) as well as with tooth agenesis (TA). These variants contribute a small risk towards… read more here.
Keywords: novel irf6; irf6 mutations; cleft; detected orofacial ... See more keywords