Tuning the pharmacokinetics and efficacy of irinotecan (IRI) loaded gelatin nanoparticles through folate conjugation.
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DOI: 10.1016/j.ijpharm.2020.119522
Abstract: Gelatin based nanocarriers have major limitation of shorter circulation half-life (t1/2). Present study addressed this issue by conjugating gelatin with folate followed by nanoprecipitation in presence of polysorbate 80 forming folate attached gelatin nanoparticles (GNP-F).… read more here.
Keywords: iri; gelatin nanoparticles; irinotecan iri; iri gnp ... See more keywords