Articles with "iri resistant" as a keyword



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Single cell mass spectrometry studies reveal metabolomic features and potential mechanisms of drug-resistant cancer cell lines.

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Published in 2022 at "Analytica chimica acta"

DOI: 10.1016/j.aca.2022.339761

Abstract: Irinotecan (Iri) is a key drug to treat metastatic colorectal cancer, but its clinical activity is often limited by de novo and acquired drug resistance. Studying the underlying mechanisms of drug resistance is necessary for… read more here.

Keywords: mechanisms drug; cancer; cell; iri resistant ... See more keywords