Association between a single nucleotide polymorphism in the R3HCC1 gene and irinotecan toxicity
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DOI: 10.1002/cam4.5299
Abstract: Irinotecan is a useful anticancer drug for colorectal cancer treatment. UGT1A1*28 and *6 gene polymorphisms are known risk factors for irinotecan‐associated toxicity. However, severe adverse effects due to irinotecan have been observed even in patients… read more here.
Keywords: irinotecan toxicity; nucleotide polymorphism; toxicity; single nucleotide ... See more keywords