Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.70117
Abstract: The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of… read more here.
Keywords: cognitive functions; correlation irisin; dementia; irisin ... See more keywords
Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202405222
Abstract: Identifying the mechanistic targets of crosstalk between sarcopenia (SA) and mild cognitive impairment (MCI) is critical for screening high‐risk populations and exploring effective prevention and treatment strategies. In a nationwide multicenter prospective cohort study combined… read more here.
Keywords: samp8 mice; muscle attenuation; muscle; irisin ... See more keywords
Investigation of the relationship between serum irisin level in the idiopathic restless legs syndrome: Could be a marker independent of physical activity?
Sign Up to like & getrecommendations! Published in 2023 at "Brain and behavior"
DOI: 10.1002/brb3.3100
Abstract: INTRODUCTION Restless legs syndrome (RLS) is a common but underdiagnosed neurological syndrome. It is characterized by the feeling of discomfort and desire to move, especially in the lower extremities, which often occurs at night, and… read more here.
Keywords: irisin; physical activity; irisin level; serum irisin ... See more keywords
Association Between Irisin Level and Cognitive Function: A Systematic Review and Meta‐Analysis
Sign Up to like & getrecommendations! Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70662
Abstract: Irisin is a newly discovered muscle factor, and more and more research has focused on the association between irisin and brain function. Our study aimed at investigating the correlation between irisin level and cognition. read more here.
Keywords: irisin level; association irisin; function; irisin ... See more keywords
FNDC5/Irisin protects neurons through Caspase3 and Bax pathways
Sign Up to like & getrecommendations! Published in 2024 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3912
Abstract: Irisin is a glycosylated protein formed from the hydrolysis of fibronectin type III domain‐containing protein 5 (FNDC5). Recent studies have demonstrated that FNDC5/Irisin is involved in the regulation of glucose and lipid metabolism, it can… read more here.
Keywords: irisin protects; bax pathways; caspase3 bax; irisin ... See more keywords
Irisin increases the expression of anorexigenic and neurotrophic genes in mouse brain
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3238
Abstract: Irisin, a newly discovered muscle‐derived hormone, acts in different organs and tissues, improving energy homeostasis. In this study, we assessed, for the first time, the effects of intraperitoneal irisin injections on circulating levels of leptin… read more here.
Keywords: increases expression; expression anorexigenic; anorexigenic neurotrophic; irisin ... See more keywords
Irisin alleviates the pyroptosis of β cells in T2DM by inhibiting NLRP3 inflammasome through regulating miR‐19b‐3p/SOCS3/STAT3 axis mediated autophagy
Sign Up to like & getrecommendations! Published in 2024 at "IUBMB Life"
DOI: 10.1002/iub.2907
Abstract: The purpose of this study was to analyze the mechanism by which irisin affects β‐cell pyroptosis in type 2 diabetes mellitus (T2DM). The in vivo T2DM model was established by raised with high‐fat diet and… read more here.
Keywords: irisin; 19b socs3; mir 19b; min6 cells ... See more keywords
Irisin Correlates Positively With BMD in a Cohort of Older Adult Patients and Downregulates the Senescent Marker p21 in Osteoblasts
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4192
Abstract: Irisin is a myokine produced by skeletal muscle during exercise in both mice and humans. We previously showed that irisin treatment ameliorates immobility‐induced osteoporosis and muscular atrophy in mice. Data in humans showed a positive… read more here.
Keywords: muscle; bmd; bone; irisin ... See more keywords
Irisin promotes cardiac progenitor cell‐induced myocardial repair and functional improvement in infarcted heart
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27037
Abstract: Irisin, a newly identified hormone and cardiokine, is critical for modulating body metabolism. New evidence indicates that irisin protects the heart against myocardial ischemic injury. However, whether irisin enhances cardiac progenitor cell (CPC)‐induced cardiac repair… read more here.
Keywords: functional improvement; progenitor cell; cardiac progenitor; irisin ... See more keywords
Irisin deficiency disturbs bone metabolism
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29894
Abstract: Balancing the process of bone formation and resorption is important in the maintenance of healthy bone. Therefore, the discovery of novel factors that can regulate bone metabolism remains needed. Irisin is a newly identified hormone‐like… read more here.
Keywords: bone; irisin; bone metabolism; irisin deficiency ... See more keywords
Role of irisin in effects of chronic exercise on muscle and bone in ovariectomized mice
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Metabolism"
DOI: 10.1007/s00774-020-01201-2
Abstract: Exercise is beneficial for the prevention and treatment of osteoporosis. Skeletal muscle affects other tissues via myokines, the release of which is regulated by acute exercise. However, the effects of chronic exercise on myokines linking… read more here.
Keywords: chronic exercise; muscle; effects chronic; bone ... See more keywords