Investigation of the relationship between serum irisin level in the idiopathic restless legs syndrome: Could be a marker independent of physical activity?
Sign Up to like & getrecommendations! Published in 2023 at "Brain and behavior"
DOI: 10.1002/brb3.3100
Abstract: INTRODUCTION Restless legs syndrome (RLS) is a common but underdiagnosed neurological syndrome. It is characterized by the feeling of discomfort and desire to move, especially in the lower extremities, which often occurs at night, and… read more here.
Keywords: irisin; physical activity; irisin level; serum irisin ... See more keywords
Irisin increases the expression of anorexigenic and neurotrophic genes in mouse brain
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3238
Abstract: Irisin, a newly discovered muscle‐derived hormone, acts in different organs and tissues, improving energy homeostasis. In this study, we assessed, for the first time, the effects of intraperitoneal irisin injections on circulating levels of leptin… read more here.
Keywords: increases expression; expression anorexigenic; anorexigenic neurotrophic; irisin ... See more keywords
Irisin Correlates Positively With BMD in a Cohort of Older Adult Patients and Downregulates the Senescent Marker p21 in Osteoblasts
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4192
Abstract: Irisin is a myokine produced by skeletal muscle during exercise in both mice and humans. We previously showed that irisin treatment ameliorates immobility‐induced osteoporosis and muscular atrophy in mice. Data in humans showed a positive… read more here.
Keywords: muscle; bmd; bone; irisin ... See more keywords
Irisin promotes cardiac progenitor cell‐induced myocardial repair and functional improvement in infarcted heart
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27037
Abstract: Irisin, a newly identified hormone and cardiokine, is critical for modulating body metabolism. New evidence indicates that irisin protects the heart against myocardial ischemic injury. However, whether irisin enhances cardiac progenitor cell (CPC)‐induced cardiac repair… read more here.
Keywords: functional improvement; progenitor cell; cardiac progenitor; irisin ... See more keywords
Irisin deficiency disturbs bone metabolism
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29894
Abstract: Balancing the process of bone formation and resorption is important in the maintenance of healthy bone. Therefore, the discovery of novel factors that can regulate bone metabolism remains needed. Irisin is a newly identified hormone‐like… read more here.
Keywords: bone; irisin; bone metabolism; irisin deficiency ... See more keywords
Role of irisin in effects of chronic exercise on muscle and bone in ovariectomized mice
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Metabolism"
DOI: 10.1007/s00774-020-01201-2
Abstract: Exercise is beneficial for the prevention and treatment of osteoporosis. Skeletal muscle affects other tissues via myokines, the release of which is regulated by acute exercise. However, the effects of chronic exercise on myokines linking… read more here.
Keywords: chronic exercise; muscle; effects chronic; bone ... See more keywords
Serum irisin levels in patients with myasthenia gravis
Sign Up to like & getrecommendations! Published in 2021 at "Neurological Sciences"
DOI: 10.1007/s10072-021-05652-x
Abstract: Myasthenia gravis (MG) is an autoimmune disorder whose main symptoms are muscle weakness and fatigue. Irisin is a novel skeletal muscle–derived myokine participating in several physiological and pathological processes. The initial objective of the project… read more here.
Keywords: irisin; irisin levels; myasthenia gravis; serum irisin ... See more keywords
Response to Letter to the Editor ‘Serum irisin concentration in patients with bladder cancer’
Sign Up to like & getrecommendations! Published in 2022 at "International Urology and Nephrology"
DOI: 10.1007/s11255-022-03215-3
Abstract: We would like to thank Dr. Kawada’s interest on our article and we are sincerely grateful to the important contributions [1, 2]. As expressed by Dr. Kawada, one important concern is that the absolute irisin… read more here.
Keywords: irisin levels; irisin; elisa kits; cancer ... See more keywords
The novel myokine irisin: clinical implications and potential role as a biomarker for sarcopenia in postmenopausal women
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine"
DOI: 10.1007/s12020-018-1814-y
Abstract: AbstractsPurposeTo clarify the association of circulating irisin with muscle, liver and bone, and to evaluate irisin as a biomarker for sarcopenia in postmenopausal women.MethodsQuadriceps cross-sectional area (QcCSA), bone mineral density (BMD), liver attenuation (measured in… read more here.
Keywords: sarcopenia postmenopausal; biomarker sarcopenia; irisin; postmenopausal women ... See more keywords
Irisin promotes osteogenic differentiation of bone marrow mesenchymal stem cells by activating autophagy via the Wnt//β-catenin signal pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Cytokine"
DOI: 10.1016/j.cyto.2020.155292
Abstract: Osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) plays a crucial role in osteoporosis. Irisin, an exercise-induced muscle-dependent myokine, has been reported to stimulate the development of brown adipose tissue and regulate energy expenditure.… read more here.
Keywords: differentiation bone; irisin; osteogenic differentiation; marrow mesenchymal ... See more keywords
A polymorphism in the Irisin-encoding gene (FNDC5) associates with hepatic steatosis by differential miRNA binding to the 3'UTR.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2018.10.021
Abstract: BACKGROUND & AIMS Irisin, the cleaved extra-cellular fragment of the Fibronectin type III domain-containing protein 5 (FNDC5) is a myokine that is proposed to have favorable metabolic activity. We aimed to elucidate the currently undefined… read more here.
Keywords: fndc5; liver; irisin; rs3480 ... See more keywords