Exerkine fibronectin type-III domain-containing protein 5/irisin-enriched extracellular vesicles delay vascular ageing by increasing SIRT6 stability.
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DOI: 10.1093/eurheartj/ehac431
Abstract: AIMS Exercise confers protection against cardiovascular ageing, but the mechanisms remain largely unknown. This study sought to investigate the role of fibronectin type-III domain-containing protein 5 (FNDC5)/irisin, an exercise-associated hormone, in vascular ageing. Moreover, the… read more here.
Keywords: irisin; fndc5; senescence; irisin enriched ... See more keywords