Lack of Adipocyte-Fndc5/Irisin Expression and Secretion Reduces Thermogenesis and Enhances Adipogenesis
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DOI: 10.1038/s41598-017-16602-z
Abstract: Irisin is a browning-stimulating molecule secreted from the fibronectin type III domain containing 5 precursor (FNDC5) by muscle tissue upon exercise stimulation. Despite its beneficial role, there is an unmet and clamorous need to discern… read more here.
Keywords: secretion; fndc5; irisin expression; fndc5 irisin ... See more keywords
Expression of Irisin/FNDC5 in Cancer Cells and Stromal Fibroblasts of Non-Small Cell Lung Cancer
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DOI: 10.3390/cancers11101538
Abstract: Background: Recent in vitro studies have indicated that irisin inhibits proliferation, migration and epithelial-mesenchymal transition. Irisin expression has not been studied in tumour tissues of non-small cell lung cancer (NSCLC) patients yet. The aim of… read more here.
Keywords: irisin expression; cancer cells; expression; lung cancer ... See more keywords
Expression of Irisin/FNDC5 in Breast Cancer
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DOI: 10.3390/ijms23073530
Abstract: Irisin is a myokine formed from fibronectin type III domain-containing protein 5 (FNDC5), which can be found in various cancer tissues. FNDC5 and irisin levels have been poorly studied in the tumor tissues of breast… read more here.
Keywords: irisin; breast; expression; irisin expression ... See more keywords