The clinical relevance of detectable plasma iron species in iron overload states and subsequent to intravenous iron‐carbohydrate administration
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DOI: 10.1002/ajh.26819
Abstract: Many disorders of iron homeostasis (e.g., iron overload) are associated with the dynamic kinetic profiles of multiple non‐transferrin bound iron (NTBI) species, chronic exposure to which is associated with deleterious end‐organ effects. Here we discuss… read more here.
Keywords: intravenous iron; iron; iron overload; iron carbohydrate ... See more keywords
Criticality of Surface Characteristics of Intravenous Iron–Carbohydrate Nanoparticle Complexes: Implications for Pharmacokinetics and Pharmacodynamics
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DOI: 10.3390/ijms23042140
Abstract: Un-complexed polynuclear ferric oxyhydroxide cannot be administered safely or effectively to patients. When polynuclear iron cores are formed with carbohydrates of various structures, stable complexes with surface carbohydrates driven by multiple interacting sites and forces… read more here.
Keywords: iron; criticality surface; iron carbohydrate; surface characteristics ... See more keywords