Tissue iron distribution in patients with anemia of inflammation: Results of a pilot study
Sign Up to like & getrecommendations! Published in 2023 at "American Journal of Hematology"
DOI: 10.1002/ajh.26909
Abstract: Anemia of inflammation (AI) is frequently present in subjects with inflammatory disorders, primarily caused by inflammation‐driven iron retention in macrophages. So far, only limited data on qualitative and quantitative estimates of tissue iron retention in… read more here.
Keywords: inflammation; iron; anemia inflammation; iron distribution ... See more keywords
Intracranial iron distribution and quantification in aceruloplasminemia: A case study.
Sign Up to like & getrecommendations! Published in 2020 at "Magnetic resonance imaging"
DOI: 10.1016/j.mri.2020.02.016
Abstract: OBJECTIVES Aceruloplasminemia (ACP) is a rare autosomal recessive disorder characterized by intracranial and visceral iron overload. With R2*-based imaging or quantitative susceptibility mapping (QSM), it is feasible to measure iron in the brain quantitatively, although… read more here.
Keywords: iron distribution; intracranial iron; iron; brain ... See more keywords
Modeling the dynamics of mouse iron body distribution: hepcidin is necessary but not sufficient
Sign Up to like & getrecommendations! Published in 2017 at "BMC Systems Biology"
DOI: 10.1186/s12918-017-0431-3
Abstract: BackgroundIron is an essential element of most living organisms but is a dangerous substance when poorly liganded in solution. The hormone hepcidin regulates the export of iron from tissues to the plasma contributing to iron… read more here.
Keywords: high iron; iron distribution; iron diet; hepcidin ... See more keywords
Stimulation of Hepatic Ferritinophagy Mitigates Irp2 Depletion-Induced Anemia
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12030566
Abstract: Background: Iron regulatory proteins (IRPs) maintain cellular iron homeostasis. Due to aberrant tissue-iron distribution, Irp2-deficient mice suffer microcytic anemia and neurodegeneration, while iron overload occurs in the liver and intestine. We previously found that Irp2… read more here.
Keywords: induced anemia; iron; stimulation hepatic; iron distribution ... See more keywords