Oxidative and glycolytic skeletal muscles deploy protective mechanisms to avoid atrophy under pathophysiological iron overload.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cachexia, sarcopenia and muscle"
DOI: 10.1002/jcsm.12897
Abstract: BACKGROUND Iron excess has been proposed as an essential factor in skeletal muscle wasting. Studies have reported correlations between muscle iron accumulation and atrophy, either through ageing or by using experimental models of secondary iron… read more here.
Keywords: iron; muscle; iron overload; skeletal muscle ... See more keywords
Iron excess affects release of NETs and ROS but does not influence other functions of neutrophils.
Sign Up to like & getrecommendations! Published in 2021 at "Immunology and cell biology"
DOI: 10.1111/imcb.12509
Abstract: Neutrophils apply several antimicrobial strategies including degranulation, phagocytosis, the generation of reactive oxygen species (ROS), and the release of neutrophil extracellular traps (NETs) to fight pathogens. Iron is considered to be an invaluable constituent of… read more here.
Keywords: nets ros; iron excess; excess affects; release nets ... See more keywords