Reduced iron export associated with hepcidin resistance can explain the iron overload spectrum in ferroportin disease
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DOI: 10.1111/liv.14539
Abstract: Ferroportin disease (FD) and hemochromatosis type 4 (HH4) are associated with variants in the ferroportin‐encoding gene SLC40A1. Both phenotypes are characterized by iron overload despite being caused by distinct variants that either mediate reduced cellular… read more here.
Keywords: iron export; iron overload; resistance; iron ... See more keywords