Experimental oral iron administration: Histological investigations and expressions of iron handling proteins in rat retina with aging.
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology"
DOI: 10.1016/j.tox.2017.10.005
Abstract: Iron is implicated in age-related macular degeneration (AMD). The aim of this study was to see if long-term, experimental iron administration with aging modifies retinal and choroidal structures and expressions of iron handling proteins, to… read more here.
Keywords: expressions iron; iron administration; age; handling proteins ... See more keywords
Tubular iron deposition and iron handling proteins in human healthy kidney and chronic kidney disease
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-27107-8
Abstract: Iron is suggested to play a detrimental role in the progression of chronic kidney disease (CKD). The kidney recycles iron back into the circulation. However, the localization of proteins relevant for physiological tubular iron handling… read more here.
Keywords: kidney; iron deposition; iron handling; iron ... See more keywords
High Iron and Iron Household Protein Contents in Perineuronal Net-Ensheathed Neurons Ensure Energy Metabolism with Safe Iron Handling
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031634
Abstract: A subpopulation of neurons is less vulnerable against iron-induced oxidative stress and neurodegeneration. A key feature of these neurons is a special extracellular matrix composition that forms a perineuronal net (PN). The PN has a… read more here.
Keywords: metabolism; ensheathed neurons; iron iron; iron handling ... See more keywords