Preferential role of iron in heme degradation of hemoglobin upon gamma irradiation.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.05.153
Abstract: It is usually believed that Îł-ray interaction with biomolecules is intermediately performed by reactive oxygen species (ROS) produced from radiolysis of water. Hemoglobin (Hb) as one of the most abundant biomolecule in blood and well-studied… read more here.
Keywords: degradation; iron heme; heme; preferential role ... See more keywords
Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-05415-4
Abstract: Obstructive sleep apnea (OSA) is a common disorder associated with increased risk of cardiovascular disease and mortality. Iron and heme metabolism, implicated in ventilatory control and OSA comorbidities, was associated with OSA phenotypes in recent… read more here.
Keywords: study; sleep apnea; heme biosynthesis; iron heme ... See more keywords
Exploring heme and iron acquisition strategies of Porphyromonas gingivalis—current facts and hypotheses
Sign Up to like & getrecommendations! Published in 2025 at "FEMS Microbiology Reviews"
DOI: 10.1093/femsre/fuaf019
Abstract: Abstract Iron and heme are crucial for pathogenic bacteria living in the human host but are not available in free form due to their binding by iron- and heme-sequestering proteins. Porphyromonas gingivalis causes dysbiosis in… read more here.
Keywords: iron acquisition; iron; heme iron; acquisition ... See more keywords
Iron/Heme Metabolism-Targeted Gallium(III) Nanoparticles Are Active against Extracellular and Intracellular Pseudomonas aeruginosa and Acinetobacter baumannii
Sign Up to like & getrecommendations! Published in 2019 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02643-18
Abstract: Iron/heme acquisition systems are critical for microorganisms to acquire iron from the human host, where iron sources are limited due to the nutritional immune system and insolubility of the ferric form of iron. Prior work… read more here.
Keywords: iii; pseudomonas aeruginosa; baumannii; iron heme ... See more keywords
PgFur participates differentially in expression of virulence factors in more virulent A7436 and less virulent ATCC 33277 Porphyromonas gingivalis strains
Sign Up to like & getrecommendations! Published in 2019 at "BMC Microbiology"
DOI: 10.1186/s12866-019-1511-x
Abstract: BackgroundPorphyromonas gingivalis is considered a keystone pathogen responsible for chronic periodontitis. Although several virulence factors produced by this bacterium are quite well characterized, very little is known about regulatory mechanisms that allow different strains of… read more here.
Keywords: a7436 less; iron heme; virulence factors; atcc 33277 ... See more keywords
Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency
Sign Up to like & getrecommendations! Published in 2017 at "Haematologica"
DOI: 10.3324/haematol.2016.151043
Abstract: Iron plays the central role in oxygen transport by erythrocytes as a constituent of heme and hemoglobin. The importance of iron and heme is also to be found in their regulatory roles during erythroblast maturation.… read more here.
Keywords: iron heme; iron; bach1; iron deficiency ... See more keywords
Towards Personalized Treatment in Haemophilia: The Role of Genetic Factors in Iron and Heme Control to Identify Patients at Risk for Haemophilic Arthropathy
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm14020145
Abstract: The treatment landscape for haemophilia is changing rapidly, creating opportunities for personalized treatment. As major morbidity is still caused by haemophilic arthropathy, understanding the factors affecting joint damage and joint damage progression might lead to… read more here.
Keywords: haemophilic arthropathy; treatment; joint damage; personalized treatment ... See more keywords