PIVOTAL trial: iron loading improves clinical outcomes
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Nephrology"
DOI: 10.1038/s41581-019-0128-5
Abstract: The PIVOTAL trial shows that proactive intravenous (i.v.) iron administration reduces cardiovascular events and deaths, transfusions and erythropoiesis-stimulating agent doses and does not increase infections in patients on haemodialysis. These findings upend the warnings of… read more here.
Keywords: loading improves; iron loading; trial iron; iron ... See more keywords
Kidney tubule iron loading in experimental focal segmental glomerulosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-05261-4
Abstract: Kidney iron deposition may play a role in the progression of tubulointerstitial injury during chronic kidney disease. Here, we studied the molecular mechanisms of kidney iron loading in experimental focal segmental glomerulosclerosis (FSGS) and investigated… read more here.
Keywords: iron loading; iron; experimental focal; loading experimental ... See more keywords
Iron loading in HFE p.C282Y homozygotes found by population screening: relationships to HLA-type and T-lymphocyte subsets
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DOI: 10.1080/00365513.2017.1342136
Abstract: Abstract Iron loading in p.C282Y homozygous HFE hemochromatosis subjects is highly variable, and it is unclear what factors cause this variability. Finding such factors could aid in predicting which patients are at highest risk and… read more here.
Keywords: cell; iron loading; number; iron ... See more keywords
Pancreatic Iron Deposition Following the Role of Iron Loading Among Transfusion Dependent Sickle Cell Disease Egyptian Children and Young Adults
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DOI: 10.1182/blood-2019-123683
Abstract: Background: Transfusion in sickle cell disease (SCD) is uncommon but a well-defined practice; either as a replacement in severe anemia or as a prophylactic therapy for its major complications mainly stroke. Differential iron loading in… read more here.
Keywords: iron loading; transfusion; iron overload; pancreatic iron ... See more keywords