Catalytic Cyclopropanation by Myoglobin Reconstituted with Iron Porphycene: Acceleration of Catalysis due to Rapid Formation of the Carbene Species.
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DOI: 10.1021/jacs.7b10154
Abstract: Myoglobin reconstituted with iron porphycene catalyzes the cyclopropanation of styrene with ethyl diazoacetate. Compared to native myoglobin, the reconstituted protein significantly accelerates the catalytic reaction and the kcat/Km value is 26-fold enhanced. Mechanistic studies indicate… read more here.
Keywords: reconstituted iron; iron porphycene; myoglobin reconstituted; myoglobin ... See more keywords