Iron regulatory protein (IRP)–mediated iron homeostasis is critical for neutrophil development and differentiation in the bone marrow
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1101/2022.03.16.483971
Abstract: Iron is mostly devoted to the hemoglobinization of erythrocytes for oxygen transport. Yet, emerging evidence points to a broader role for the metal in hematopoiesis, including the formation of the immune system. Iron availability in… read more here.
Keywords: development differentiation; iron; neutrophil development; iron regulatory ... See more keywords
The Discovery of the Iron-Regulatory Hormone Hepcidin.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical chemistry"
DOI: 10.1373/clinchem.2019.306407
Abstract: Featured Article: Park CH, Valore EV, Waring AJ, Ganz T. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem 2001;276:7806–10.2 Louis Pasteur's adage “Chance favors only the prepared mind” is a romantic… read more here.
Keywords: iron regulatory; discovery iron; regulatory hormone; hormone hepcidin ... See more keywords
6-Hydroxydopamine Induces Abnormal Iron Sequestration in BV2 Microglia by Activating Iron Regulatory Protein 1 and Inhibiting Hepcidin Release
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12020266
Abstract: Disrupted iron homeostasis in the substantia nigra pars compacta (SNpc) is an important pathological mechanism in Parkinson’s disease (PD). It is unclear what role microglia play in iron metabolism and selective iron deposition in the… read more here.
Keywords: iron; iron regulatory; expression; release ... See more keywords