Paradoxical Increase of Insulin Sensitivity Despite Blunted Adipose Tissue Browning in Genetic Ablation of IRP1 (OR09-08-19).
Sign Up to like & getrecommendations! Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz041.or09-08-19
Abstract: Objectives Iron regulatory protein 1 (IRP1) plays a key regulator of cellular iron metabolism, systemic oxygen sensing, and erythropoiesis. Deletion of IRP1 leads to profound HIF2a-dependent abnormalities in erythropoiesis and iron metabolism. Previously, we demonstrated… read more here.
Keywords: tissue browning; irp1; insulin sensitivity; adipose tissue ... See more keywords
The secreted peptide IRP1 functions as a phytocytokine in rice immunity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of experimental botany"
DOI: 10.1093/jxb/erac455
Abstract: Small signaling peptides play important roles in various plant processes, but information regarding their involvement in plant immunity is limited. We previously identified a novel small secreted protein in rice, named immune response peptide 1… read more here.
Keywords: irp1; rice immunity; peptide irp1; rice ... See more keywords
Human IRP1 Translocates to the Nucleus in a Cell-Specific and Iron-Dependent Manner
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DOI: 10.3390/ijms231810740
Abstract: Iron regulatory protein 1 (IRP1) is a bifunctional protein with mutually exclusive RNA-binding or enzymatic activities that depend on the presence of a 4Fe-4S cluster. While IRP1 is a well-established cytosolic protein, work in a… read more here.
Keywords: irp1; iron; iron dependent; nuclear irp1 ... See more keywords