Protective Effects of Hif2 Inhibitor PT-2385 on a Neurological Disorder Induced by Deficiency of Irp2
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DOI: 10.3389/fnins.2021.715222
Abstract: Iron regulatory protein 2 (IRP2) deficiency in mice and humans causes microcytic anemia and neurodegeneration due to functional cellular iron depletion. Our previous in vitro data have demonstrated that Irp2 depletion upregulates hypoxia-inducible factor subunits… read more here.
Keywords: neurological disorder; glycolysis; irp2; hif2 ... See more keywords