Local Release of TGF‐β Inhibitor Modulates Tumor‐Associated Neutrophils and Enhances Pancreatic Cancer Response to Combined Irreversible Electroporation and Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202105240
Abstract: Pancreatic cancer is a deadly disease with little response to standard therapies. Irreversible electroporation (IRE) has emerged as a novel ablative technique for the clinical treatment of pancreatic cancer. Combinations of IRE and immunotherapies, including… read more here.
Keywords: response; pancreatic cancer; enhances pancreatic; irreversible electroporation ... See more keywords
Irreversible electroporation for the ablation of pancreatic malignancies: A patient‐specific methodology
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.24566
Abstract: Irreversible Electroporation (IRE) is a focal ablation technique highly attractive to surgical oncologists due to its non‐thermal nature that allows for eradication of unresectable tumors in a minimally invasive procedure. In this study, our group… read more here.
Keywords: irreversible electroporation; methodology; ablation; electroporation ablation ... See more keywords
Physical and Chemical Enhancement of and Adaptive Resistance to Irreversible Electroporation of Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Biomedical Engineering"
DOI: 10.1007/s10439-017-1932-3
Abstract: Irreversible electroporation (IRE) can be used to treat cancer by electrical pulses, with advantages over traditional thermal approaches. Here we assess for the first time the IRE response of pancreatic cancer, one of the deadliest… read more here.
Keywords: irreversible electroporation; ire; pancreatic cancer; adaptive resistance ... See more keywords
Ultrasound-guided percutaneous irreversible electroporation of hepatic and abdominal tumors not eligible for surgery or thermal ablation: a western report on safety and efficacy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Ultrasound"
DOI: 10.1007/s40477-019-00372-7
Abstract: PurposeTo report our first results on sixteen patients affected by liver and abdominal malignant tumors, unfit for surgery or thermal ablation, treated with US-guided percutaneous irreversible electroporation (IRE).MethodsFrom June 2014 to December 2016, all patients… read more here.
Keywords: irreversible electroporation; ablation; thermal ablation; abdominal tumors ... See more keywords
Irreversible electroporation inhibits pro-cancer inflammatory signaling in triple negative breast cancer cells.
Sign Up to like & getrecommendations! Published in 2017 at "Bioelectrochemistry"
DOI: 10.1016/j.bioelechem.2016.09.003
Abstract: Low-level electric fields have been demonstrated to induce spatial re-distribution of cell membrane receptors when applied for minutes or hours. However, there is limited literature on the influence on cell signaling with short transient high-amplitude… read more here.
Keywords: irreversible electroporation; negative breast; breast cancer; cancer ... See more keywords
Advantages and limitations of various treatment chamber designs for reversible and irreversible electroporation in life sciences.
Sign Up to like & getrecommendations! Published in 2021 at "Bioelectrochemistry"
DOI: 10.1016/j.bioelechem.2021.107841
Abstract: The fundamental mechanisms of pulsed electric fields on biological cells are not yet fully elucidated, though it is apparent that membrane electroporation plays a crucial role. Little is known about treatment-chamber-specific effects, and systematic studies… read more here.
Keywords: irreversible electroporation; chamber; treatment chamber; electroporation ... See more keywords
Irreversible Electroporation in Hepatopancreaticobiliary Tumours
Sign Up to like & getrecommendations! Published in 2018 at "Canadian Association of Radiologists Journal"
DOI: 10.1016/j.carj.2017.10.005
Abstract: Hepatopancreaticobiliary tumours are often diagnosed at an advanced disease stage, in which encasement or invasion of local biliary or vascular structures has already occurred. Irreversible electroporation (IRE) is an image-guided tumour ablation technique that induces… read more here.
Keywords: irreversible electroporation; electroporation hepatopancreaticobiliary; hepatopancreaticobiliary tumours;
Initial experience with irreversible electroporation of liver tumours
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Radiology Open"
DOI: 10.1016/j.ejro.2019.01.004
Abstract: Introduction Thermal ablation of liver tumours is an established technique used in selected patients with relatively small tumours that can be ablated with margin. Thermal ablation methods are not advisable near larger bile ducts that… read more here.
Keywords: irreversible electroporation; liver tumours; thermal ablation; liver ... See more keywords
3D planning of irreversible electroporation treatment in pancreatic carcinoma: a use case
Sign Up to like & getrecommendations! Published in 2018 at "Hpb"
DOI: 10.1016/j.hpb.2018.06.2299
Abstract: Irreversible-electroporation (IRE) is an ablation technique that spares vessels and is therefore suitable for treatment of locally advanced pancreatic cancer. Our surgery planning software supports pre-operative simulation of possible needle configurations in 3D to prepare… read more here.
Keywords: irreversible electroporation; treatment; electroporation treatment; treatment pancreatic ... See more keywords
Maxwell's equations explain why irreversible electroporation will not heat up a metal stent
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Heat and Mass Transfer"
DOI: 10.1016/j.ijheatmasstransfer.2021.120962
Abstract: Abstract Irreversible Electroporation (IRE) is a promising clinical ablation therapy for the treatment of cancer, but issues with the generation of heat must be solved before safe and effective clinical results can be obtained. In… read more here.
Keywords: heat; metal stent; maxwell equations; irreversible electroporation ... See more keywords
Irreversible electroporation for locally advanced pancreatic cancer through a minimally invasive surgery supported by laparoscopic ultrasound
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Surgery Case Reports"
DOI: 10.1016/j.ijscr.2017.12.036
Abstract: Highlights • We report on the application of Irreversible electroporation (IRE) on locally advanced pancreatic cancer (LAPC).• We report on a minimally invasive surgical approach supported by laparoscopic ultrasound.• We report on a novel technique… read more here.
Keywords: irreversible electroporation; minimally invasive; advanced pancreatic; supported laparoscopic ... See more keywords