Irreversible Enzyme Inhibition Kinetics and Drug-Drug Interactions.
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DOI: 10.1007/978-1-0716-1554-6_3
Abstract: This chapter describes the types of irreversible inhibition of drug-metabolizing enzymes and the methods commonly employed to quantify the irreversible inhibition and subsequently predict the extent and time course of clinically important drug-drug interactions. read more here.
Keywords: drug interactions; enzyme inhibition; inhibition; irreversible enzyme ... See more keywords