Articles with "irreversible mutant" as a keyword



Photo from wikipedia

Abstract 2079: Osimertinib, an irreversible mutant selective EGFR tyrosine kinase inhibitor, exerts anti tumor activity in NSCLC harbouring exon 20 insertion mutant-EGFR

Sign Up to like & get
recommendations!
Published in 2017 at "Cancer Research"

DOI: 10.1158/1538-7445.am2017-2079

Abstract: EGFR exon 20 insertion (Ex20Ins) mutations represent a combination of in-frame insertions and/or duplications that account for 4-10% of all EGFR mutants in non-small cell lung cancer (NSCLC). To date, more than one hundred different… read more here.

Keywords: tumor; egfr; irreversible mutant; exon insertion ... See more keywords