IRX5 promotes colorectal cancer metastasis by negatively regulating the core components of the RHOA pathway
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23098
Abstract: Colorectal cancer (CRC) is one of the most common malignant tumors worldwide. As tumor metastasis is the leading cause of death in patients with CRC, it is important to elucidate the molecular mechanisms that drive… read more here.
Keywords: irx5; colorectal cancer; metastasis; irx5 promotes ... See more keywords
Id2 Determines Intestinal Identity through Repression of the Foregut Transcription Factor Irx5
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00250-17
Abstract: ABSTRACT The cellular components and function of the gastrointestinal epithelium exhibit distinct characteristics depending on the region, e.g., stomach or intestine. How these region-specific epithelial characteristics are generated during development remains poorly understood. Here, we… read more here.
Keywords: id2; determines intestinal; irx5; epithelium ... See more keywords