Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103006
Abstract: A series of novel tacrine-isatin Schiff base hybrid derivatives (7a-p) were designed, synthesized and evaluated as multi-target candidates against Alzheimer's disease (AD). The biological assays indicated that most of these compounds displayed potent inhibitory activity… read more here.
Keywords: ache; tacrine isatin; isatin schiff; tacrine ... See more keywords
Experimental and theoretical studies on isatin-Schiff bases and their copper(II)-complexes: Syntheses, spectroscopy, tautomerism, redox potentials, EPR, PXRD and DFT/TDDFT
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DOI: 10.1016/j.molstruc.2019.127207
Abstract: Abstract The isatin-Schiff bases 3-(o/p-tolylimino)indolin-2-one (HL1 and HL2) react with the copper(II) acetate or nitrate to give the bis[3-(o/p-tolylimino)indole-2-olato-κ2N,O]copper(II) (1 and 2) via lactam (L)- to enol (E)-tautomerism in solution. IR spectra show solely the… read more here.
Keywords: schiff bases; copper complexes; tautomerism; copper ... See more keywords
Green synthesis, antibacterial evaluation and QSAR analysis of some isatin Schiff bases
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DOI: 10.1016/j.molstruc.2020.127853
Abstract: Abstract Twelve isatin Schiff bases (1a-7a, 1b-5b) were prepared by reacting isatin and 5-bromoisatin with different anilines using green chemistry (microwave (MW) and ultrasound (US) assisted synthesis). The antibacterial activity of each compound was evaluated… read more here.
Keywords: schiff bases; isatin; synthesis antibacterial; qsar analysis ... See more keywords
Fe-MIL-101 modified by isatin-Schiff-base-Co: a heterogeneous catalyst for C–C, C–O, C–N, and C–P cross coupling reactions
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DOI: 10.1039/d1nj03468e
Abstract: Fe-MIL-101-isatin-Schiff-base-Co was synthesized and applied as a catalyst for Ullmann-type, Buchwald–Hartwig, Hirao, Hiyama and Mizoroki–Heck cross-coupling reactions of aryl halides. read more here.
Keywords: mil 101; isatin schiff; coupling reactions; cross coupling ... See more keywords